Portfolio

FEATURED POPULAR SCIENCE WRITING

Swallow the Micro-RobotNEO.LIFE | December 16, 2021

What Do Neurons and Snowflakes Have to Teach Us About AI? | NEO.LIFE | November 18, 2021

Is Your Exoskeleton Ready for Primetime? | NEO.LIFE | October 28, 2021

Shooting for Longevity and the Stars | NEO.LIFE | October 14, 2021

Enabling Scientific Discovery and Healthcare with Biobanks | GEN | November 3, 2020

Expanding the CRISPR Toolbox | GEN | March 1, 2020

June Lab Delivers CRISPR Safety Message in Cancer Clinical Trial | GEN |February 6, 2020

How to Use CRISPR for Site-Specific Epigenetic Editing in the Nervous System | GEN | November 13, 2019

How To Synthesize Stable Lifeforms For The Long Run | Medium | September 05, 2019

Is Sexual Orientation Encoded In Our DNA? | Medium | August 29, 2019

A New Way to Detect Parkinson’s—by Smell | Scientific American | April 10, 2019

The One Change That Boosts a High School’s Academic Performance | Scientific American | February 12, 2019

A New Connection between the Gut and the Brain | Scientific American | December 5, 2018

How Exercise Might “Clean” the Alzheimer’s Brain | Scientific American | October 16, 2018

COMPANY PROFILES

From Junk to Treasure: Syros Pharmaceuticals Mines Non-Coding DNA to Treat DiseaseGEN Edge | October 12, 2021

Pardes Biosciences Advances Oral Antiviral Drug for SARS-CoV-2 InfectionsGEN Edge | October 5, 2021

Go Your Own Way: Vector Laboratories Completes $124 Million Buyout and Initiates Acquisition StrategyGEN Edge | October 1, 2021

Needles and Pills: Rani Therapeutics Is Making Encapsulated Oral BiologicsGEN Edge | September 7, 2021

I Can See Clearly Now: Seer Creates a Transformative View of the Protein PanoramaGEN Edge | August 18, 2021

Creating a Clinical Crystal Ball: SOPHiA Genetics is Democratizing Data-Driven MedicineGEN Edge | August 9, 2021

The Upregulation Revolution: CAMP4’s Climb to Reach Untouched Diseases by Dialing Up Gene Expression GEN Edge |  July 27, 2021

Breaker of Chains: Karuna Therapeutics Challenges Antipsychotic Drug BarrierGEN Edge | July 22, 2021

By Decoding Patient Drug Responses, Scipher Medicine Tackles Wasteful Healthcare SpendingGEN Edge | July 20, 2021

We Have Lift Off: Codiak BioSciences Bears Down with Exosomes as a Therapeutic ModalityGEN Edge | June 10, 2021

Designer Genes: Synlogic Is Crafting Living Therapeutics Programmed to Treat DiseaseGEN Edge | 10, 2021

One in a Million: Homology Medicines Targets New Approach for Rare Genetic DiseasesGEN Edge | June 9, 2021

Heavyweight Division: Arvinas Paves the Way for Therapeutics That Degrade Disease-Related ProteinsGEN Edge | May 21, 2021

Celularity: Productizing Placental-Derived Stem Cells for Any PatientGEN Edge | April 28, 2021

A Ruby in the Rough: Rubius Therapeutics Transforms Red Blood Cells into Cellular MedicinesGEN Edge | April 22, 2021

Let There Be Light: GreenLight Strives for Global RNA Equity to Solve Health and Agricultural ProblemsGEN Edge | April 15, 2021

It’s a tRNA World: How aTyr Transformed tRNA Synthetases into Clinical Stage MedicinesGEN Edge | March 23, 2021

Shooting the Messenger: Locanabio Writes a New Script for RNA DiseasesGEN Edge | January 7, 2021

Alexa, Make Me a Protein: Denovium’s AI Reimagines De Novo ProteinsGEN Edge | December 22, 2021

23 Trillion and Me: Persephone Biosciences Harnesses the Gut Microbiome to Treat DiseaseGEN Edge | December 9, 2020

X and Y: Synthorx Expands the Genetic Code to Create Optimized BiologicsGEN Edge | November 19, 2020

Can Encodia Become the Illumina of Proteomics?GEN Edge | November 5, 2020

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Research Publications

Zhang Y, Li T, Preissl S, Amaral ML, Grinstein JD, Farah EN, Destici E, Qiu Y, Hu R, Lee AY, Chee S, Ma K, Ye Z, Zhu Q, Huang H, Fang R, Yu L, Izpisua Belmonte JC, Wu J, Evans SM, Chi NC, Ren B. Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells. Nat Genet. 2019 Sep;51(9):1380-1388. doi: 10.1038/s41588-019-0479-7.

Veevers J, Farah EN, Corselli M, Witty AD, Palomares K, Vidal JG, Emre N, Carson CT, Ouyang K, Liu C, van Vliet P, Zhu M, Hegarty JM, Deacon DC, Grinstein JD, Dirschinger RJ, Frazer KA, Adler ED, Knowlton KU, Chi NC, Martin JC, Chen J, Evans SM. Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells. Stem Cell Reports. 2018. doi: 10.1016/j.stemcr.2018.07.007.

Panopoulos AD, D’Antonio M, Arias AD, Benaglio P, DeBoever C, Williams R, Garcia M, Nelson B, Harismendy O, Grinstein JD, Drees F, Okubo J, Diffenderfer KE, Hishida Y, Modesto V, Dargitz CT, Feiring R, Zhao C, Jepsen K, McGarry T, Matsui H, Reyna J, Aguirre A, Rao F, O’Connor DT, Chi NC, Goldstein LS, Izpisua Belmonte JC, Berggren WT, Adler E, D’Antonio-Chronowska A, Smith EN, Frazer KA. iPSCORE: A systematically derived resource of iPSC lines from 222 individuals for use in examining how genetic variation affects molecular and physiological traits across a variety of cell types. Stem Cell Reports. 2017. doi: 10.1016/j.stemcr.2017.03.012.

Han P, Bloomekatz J, Ren J, Zhang R, Grinstein JD, Zhao L, Burns CG, Burns CE, Anderson RM, Chi NC. Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 2016. doi: 10.1038/nature18310.

Lacombe J, Hanley O, Jung H, Philippidou P, Surmeli G, Grinstein JD, Dasen JS. Dev. Cell. 2013. Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLoS Genet. 2013. doi: 10.1371/journal.pgen.1003184.

Yang L, Lin C, Liu W, Zhang J, Ohgi KA, Grinstein JD, Dorrestein PC, Rosenfeld MG. ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell. 2011. doi: 10.1016/j.cell.2011.08.054.

Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein JD, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS. Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010. doi: 10.1016/j.neuron.2010.08.008.