Genetic Engineering & Biotechnology News (GEN)

Enabling Scientific Discovery and Healthcare with Biobanks | November 3, 2020

Expanding the CRISPR Toolbox | March 1, 2020

June Lab Delivers CRISPR Safety Message in Cancer Clinical TrialFebruary 6, 2020

How to Use CRISPR for Site-Specific Epigenetic Editing in the Nervous System | November 13, 2019


GEN Edge

From Junk to Treasure: Syros Pharmaceuticals Mines Non-Coding DNA to Treat Disease | October 12, 2021

Pardes Biosciences Advances Oral Antiviral Drug for SARS-CoV-2 Infections | October 5, 2021

Go Your Own Way: Vector Laboratories Completes $124 Million Buyout and Initiates Acquisition Strategy | October 1, 2021

Needles and Pills: Rani Therapeutics Is Making Encapsulated Oral Biologics | September 7, 2021

I Can See Clearly Now: Seer Creates a Transformative View of the Protein Panorama | August 18, 2021

Creating a Clinical Crystal Ball: SOPHiA Genetics is Democratizing Data-Driven Medicine | August 9, 2021

The Upregulation Revolution: CAMP4’s Climb to Reach Untouched Diseases by Dialing Up Gene Expression | July 27, 2021

Breaker of Chains: Karuna Therapeutics Challenges Antipsychotic Drug Barrier | July 22, 2021

By Decoding Patient Drug Responses, Scipher Medicine Tackles Wasteful Healthcare Spending | July 20, 2021

We Have Lift Off: Codiak BioSciences Bears Down with Exosomes as a Therapeutic Modality | June 10, 2021

Designer Genes: Synlogic Is Crafting Living Therapeutics Programmed to Treat Disease | June 10, 2021

One in a Million: Homology Medicines Targets New Approach for Rare Genetic Diseases | June 9, 2021

Heavyweight Division: Arvinas Paves the Way for Therapeutics That Degrade Disease-Related Proteins | May 21, 2021

Celularity: Productizing Placental-Derived Stem Cells for Any Patient | April 28, 2021

A Ruby in the Rough: Rubius Therapeutics Transforms Red Blood Cells into Cellular Medicines | April 22, 2021

Let There Be Light: GreenLight Strives for Global RNA Equity to Solve Health and Agricultural Problems | April 15, 2021

It’s a tRNA World: How aTyr Transformed tRNA Synthetases into Clinical Stage Medicines | March 23, 2021

Shooting the Messenger: Locanabio Writes a New Script for RNA Diseases | January 7, 2021

Alexa, Make Me a Protein: Denovium’s AI Reimagines De Novo Proteins | December 22, 2021

23 Trillion and Me: Persephone Biosciences Harnesses the Gut Microbiome to Treat Disease | December 9, 2020

X and Y: Synthorx Expands the Genetic Code to Create Optimized Biologics | November 19, 2020

Can Encodia Become the Illumina of Proteomics? | November 5, 2020



How To Synthesize Stable Lifeforms For The Long Run | September 05, 2019

Is Sexual Orientation Encoded In Our DNA? | August 29, 2019



Shooting for Longevity and the Stars | October 14, 2021


Neuroleadership Institute

4 Ways to Honor (or Overwhelm) Your Employees’ Cognitive Capacity | June 9, 2020

Cultivate Your Growth Mindset to Thrive Through Crisis | May 20, 2020

3 Psychological Habits to Deliver What Matters During a Crisis | May 7, 2020

How to Be Optimistic and Realistic During the COVID-19 Pandemic | April 24, 2020

Focusing the Public Sector in a Telework World | March 24, 2020

What the Challenger Disaster Teaches Us About Speaking Up In A New Era Of Spaceflight | February 27, 2020



Why NAD+ Declines With Age | October 22, 2021

Telomere Length and Aging | October 4, 2021

What’s the Difference Between Aging and Longevity? | September 14, 2021

How Do I Find Out My Biological Age? | September 8, 2021

Fido Forever: Figuring Out How to Treat Aging in Dogs Can Help People Live Longer and Healthier | August 30, 2021

Super-Heroes and Ultra-Healers: The Real-World Science of Deadpool’s Immortality | August 10, 2021

Can Organ Transplantation Help You Live Forever? | May 12, 2021

What are Senescent Cells and Why are They Being Targeted for Healthier Aging? | April 14, 2021


Science 101

Mindfulness meditation mends mild cognitive impairment | November 27, 2019

This is your brain on Black Friday | November 26, 2019

The race to stop cat allergies | October 29, 2019

AI learns to solve Rubik’s Cube without human help | October 29, 2019

Smartphones and Fitbits can spot loneliness in its tracks | October 2, 2019

Human sexes use their whole genomes distinctively | August 28, 2019

Athletes make performance enhancing gut microbes | August 13, 2019

Brain stimulation revives working memory in older adults | July 18, 2019

Becoming plastic people: a survey on microplastics consumption | July 18, 2019

Spores squash malaria mosquitos with spider venom | June 13, 2019

Seeing the twilight zone in technicolor through deep sea fish eyes | June 6, 2019

Seaworm species recently evolved the ability to regenerate heads — brains included | June 3, 2019

Sounding out ear infections with smartphones and paper | May 28, 2019

How to artificially implant a memory, ‘Inception’-style | May 20, 2019

The brain’s unique ‘drain system’ could flush Alzheimer’s | May 13, 2019


Scientific American

A New Way to Detect Parkinson’s—by Smell | April 10, 2019

The One Change That Boosts a High School’s Academic Performance | February 12, 2019

A New Connection between the Gut and the Brain | December 5, 2018

How Exercise Might “Clean” the Alzheimer’s Brain | October 16, 2018


Science Marketing & PR

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Research Publications

Zhang Y, Li T, Preissl S, Amaral ML, Grinstein JD, Farah EN, Destici E, Qiu Y, Hu R, Lee AY, Chee S, Ma K, Ye Z, Zhu Q, Huang H, Fang R, Yu L, Izpisua Belmonte JC, Wu J, Evans SM, Chi NC, Ren B. Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells. Nat Genet. 2019 Sep;51(9):1380-1388. doi: 10.1038/s41588-019-0479-7. 

Veevers J, Farah EN, Corselli M, Witty AD, Palomares K, Vidal JG, Emre N, Carson CT, Ouyang K, Liu C, van Vliet P, Zhu M, Hegarty JM, Deacon DC, Grinstein JD, Dirschinger RJ, Frazer KA, Adler ED, Knowlton KU, Chi NC, Martin JC, Chen J, Evans SM. Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells. Stem Cell Reports. 2018. doi: 10.1016/j.stemcr.2018.07.007.

Panopoulos AD, D’Antonio M, Arias AD, Benaglio P, DeBoever C, Williams R, Garcia M, Nelson B, Harismendy O, Grinstein JD, Drees F, Okubo J, Diffenderfer KE, Hishida Y, Modesto V, Dargitz CT, Feiring R, Zhao C, Jepsen K, McGarry T, Matsui H, Reyna J, Aguirre A, Rao F, O’Connor DT, Chi NC, Goldstein LS, Izpisua Belmonte JC, Berggren WT, Adler E, D’Antonio-Chronowska A, Smith EN, Frazer KA. iPSCORE: A systematically derived resource of iPSC lines from 222 individuals for use in examining how genetic variation affects molecular and physiological traits across a variety of cell types. Stem Cell Reports. 2017. doi: 10.1016/j.stemcr.2017.03.012.

Han P, Bloomekatz J, Ren J, Zhang R, Grinstein JD, Zhao L, Burns CG, Burns CE, Anderson RM, Chi NC. Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 2016. doi: 10.1038/nature18310.

Lacombe J, Hanley O, Jung H, Philippidou P, Surmeli G, Grinstein JD, Dasen JS. Dev. Cell. 2013. Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLoS Genet. 2013. doi: 10.1371/journal.pgen.1003184.

Yang L, Lin C, Liu W, Zhang J, Ohgi KA, Grinstein JD, Dorrestein PC, Rosenfeld MG. ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell. 2011. doi: 10.1016/j.cell.2011.08.054.

Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein JD, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS. Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010. doi: 10.1016/j.neuron.2010.08.008.